The sympathetic nervous system will cause vasodilation in the arteries of many blood vessels, but vasoconstriction in the brain. Why does this occur?
The sympathetic nervous system exerts its effect on blood
vessels by releasing adrenaline and noradrenaline.
These two catecholamines binds to the adrenergic receptors present
in the blood vessels. Blood vessels contains alpha as well as beta
adrenergic receptors. Binding of adrenaline to alpha adrenergic
receptors results in vasoconstriction while binding to beta
adrenergic receptors cause vasodilatation. If a blood vessel
contains more of beta adrenergic receptors it will vasodilate to
the action of sympathetic nervous system and if a blood vessel
contains more of alpha adrenergic receptors it will
vasoconstrict.
The vasoconstriction of blood vessels of brain during sympathetic
stimulation helps limit excess blood flow to the brain and thus
regulates the peripheral resistance and blood pressure in brain.
Excess blood flow yo brain causes disruption of blood brain
barrier.
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