Question

need quick answer

You have recently graduated and are working for a new pharmaceutical company developing a drug to prolong the action of a neurotransmitter at a chemical synapse. Which of the following drugs should meet this goal?

Group of answer choices

A drug that is a blocker of the enzymatic degradation of the neurotransmitter in the synaptic cleft.

A drug that is a postsynaptic receptor blocker.

Two of these answers

A drug is a blocker of the presynaptic synthesis of the neurotransmitter.

A drug that is a blocker of the presynaptic reuptake of the neurotransmitter.

Answer 1

Answer

Option C) Two of these answers

• There are three methods that removes neurotransmitter from the synaptic cleft :
  • Diffusion of neurotransmitter away from the synapse
  • Enzymatic degradation
  • Reuptake by presynaptic membrane
• In order to prolong the action of a neurotransmitter, it is important to prevent removal of neurotransmitter from the synaptic cleft.
• Hence,
  - A drug that is a blocker of the enzymatic degradation of the neurotransmitter in the synaptic cleft and
  - A drug that is a blocker of the presynaptic reuptake of the neurotransmitter
  will help to extend the effects of neurotransmitter.