Question

35. Carbamazepine toxicity is associated with which of the following allele variant? A. HLA-B*57:01 B. HLA-C*14:29...

35. Carbamazepine toxicity is associated with which of the following allele variant?

A. HLA-B*57:01

B. HLA-C*14:29

C.HLA-B*15:02

D.CYP2C19*3

Homework Answers

Answer #1

HLA-B*15:02

  • Carbamazepine is a drug used for the treatment of eiplepsy.
  • Human leukocyte antigen , HLA-B*15:02 is an allele which is associated with overdose of carbamazepine.
  • HLA is a protein , which play an important role in immune response.
  • Option A is wrong because HLA-B*57:01 is associated withdrug induced liver toxicity which include antiretroviral drugs.
  • Option B is wrong because HLA-C*14:29 is a MHC molecule .
  • Option D is wrong because CYP2C19*3 is associated with alzheimer's disease.
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
Which of the following is a dose-limiting toxicity of paclitaxel? a Severe nephrotoxicity b Arrhythmia c...
Which of the following is a dose-limiting toxicity of paclitaxel? a Severe nephrotoxicity b Arrhythmia c Hepatotoxicity d Hypersensitivity reaction
34. Which of the following techniques uses capillary gel electrophoresis as an allele detection to distancing...
34. Which of the following techniques uses capillary gel electrophoresis as an allele detection to distancing between the reference allele and the variant one? A. Sanger DNA sequencing B. PCR-RFLP C. Pyrosequencing D. Tag Man
Find the following: a) Z.99   b) Z.02 c) Z.90 d) Z.01
Find the following: a) Z.99   b) Z.02 c) Z.90 d) Z.01
Which of the following antipsychotic drugs has least extrapyramidal toxicity: Select one: a. Chlorpromazine b. Fluphenazine...
Which of the following antipsychotic drugs has least extrapyramidal toxicity: Select one: a. Chlorpromazine b. Fluphenazine c. Haloperidol d. Clozapine can you solve it as soon as possible thank you rawand
Which of the following is associated with the Limbic System? A.  ataxia B. aphasia C. coma D....
Which of the following is associated with the Limbic System? A.  ataxia B. aphasia C. coma D. manic-depression E. resting muscle tremors
Consider the following possible outcomes for the economy (first column) with the associated probabilities (second column)...
Consider the following possible outcomes for the economy (first column) with the associated probabilities (second column) and the return of stock A for the different states of the world. Outcome Probability Return Recession 25% -30% Expansion 40% 15% Boom 35% 55% What is the expected variance of stock A? a. 11% b. 6% c. 29%
Which of the following are prostaglandins NOT associated with? a. reproductive processes b. inflamation and fever...
Which of the following are prostaglandins NOT associated with? a. reproductive processes b. inflamation and fever c. blood clotting d. absorption of Na+ by the kidneys
29. Which would be isotropic: (a) a nylon filament, (b) an extruded pipe, or (c) ebonite?...
29. Which would be isotropic: (a) a nylon filament, (b) an extruded pipe, or (c) ebonite? 30. Which will have the higher relaxation time: (a) unvulcanized rubber or (b) ebonite? 31. In which element or model for a viscoelastic body, (a) Maxwell or (b) Voigt–Kelvin, will the elastic response be retarded by viscous resistance? 33. Which of the following might you expect would increase their conductivity when doped: (a) PS, (b) PPO, (c) nylon 66, or (d) aramids?
A price-weighted index consists of stocks A, B, and C which are priced at $50, $35,...
A price-weighted index consists of stocks A, B, and C which are priced at $50, $35, and $15 a share, respectively. The current index divisor is 2.75. What will the new index advisor be if stock A undergoes a 5-for-1 stock split? A. 0.40 B. 0.65 C. 1.00 D. 1.65
45. Which of the following is not associated with federal government debt? a. Liquidity risk b....
45. Which of the following is not associated with federal government debt? a. Liquidity risk b. Default risk c. Maturity Risk d. Both a & b