Question

4. Explain the feedback mechanism of thyroid hormone. Start by identifying the different structures that are...

4. Explain the feedback mechanism of thyroid hormone. Start by identifying the different structures

that are involved in the brain and the periphery. What substances (hormones) are released in

response to each of these? DO NOT DRAW EXPLAIN PLEASE

Science   Anatomy-And-Physiology   
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Answer #1

1. In response to an external stimulus such as cold exposure, the hypothalamus secretes thyrotropin releasing hormone (TRH).
2. TRH acts on the anterior pituitary gland and stimulates the secertion of Thyroid stimulating hormone (TSH)
3. TSH acts on the thyroid gland and stimulates the secertion of Thyroid hormones such as T3 and T4.
4. T3 and T4 acts on various body tissues and promote the overall metabolism.

Thyroid hormones exhibit a negative feedback effect on abterior pituitary to inhibit the TSH secretion.
They also inhibit the secretion of TRH from the hypothalamus.

The negative feedback mechanism ensures that a proper signaling level is maintained.

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