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Describe the intracellular events that occur in a neuron once an action potential reaches a synaptic...

Describe the intracellular events that occur in a neuron once an action potential reaches a synaptic end bulb.

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Answer #1
  • Once the action potential reaches the synaptic end bulb.
  • The action potential cause the depolarizatiom of the membrane.
  • Due to the depolarizatiom the voltage-gated sodium channels are opened and sodium enters to the cell.
  • Then the further depolarizatiom occurs on the membrane.
  • Which cause the opening of calcium channels, calcium ions enters to the cell and initiates the signalling processes.
  • Calcium will interact with SNARE protein within the synapse.
  • These interactions between the SNARE protein causes the membrane fusion. The synaptic end bulb or synaptic vesicle fused with axon terminal.
  • This fusion cause the release of neurotransmitters to the synaptic cleft.
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