Question

The following UA was collected in the Emergency Room and was immediately tested. dipstick results were Nitrite= negative, LE=negative, Blood = large The patients microscopic results were as follows: 10-30 WBC's, 3+ Gram Positive Bacteria and 0-5 RBC's What would cause the inconsistencies between the 3 dipstick results and microscopic results

Answer 1

inconsistencies between dipstick test and microscopic result

ACCORDING TO MICROSCOPIC RESULT

URINARY TRACT INFECTION IS PRESENT

NITRITE IS NEGATIVE,IT CAN BE FALSE NEGATIVE IN CASE OF

• High specific gravity,
• ascorbic acid,
• oxalic acid,
• Lodine,
• formalin,
• chlorhexidine,
• factors that inhibit or prevent nitrite formation despite bacteriuria

LEUKOCYTE ESTERASE IS NEGATIVE ,IT CAN BE FALSE NEGATIVE IN CASE OF

• ascorbic acid,
• boric acid,
• strong oxidizing agents,
• quinidine,
• Tagamet,
• chloroquine,
• sulfamethoxazole,
• chlorhexidine,
• nitrofurantoin,
• Lodine,

BLOOD IS LARGE IT CAN BE FALSE POSITIVE

• Peroxidases
• strong oxidizing agents

MICROSCOPIC ANALYSIS OF URINE SUGGEST

• LEUKOCYTES suggest presence of infection
• 3+ gram positive suggest presence of the Gram-positive bacteria Staphylococcus saprophyticus, Enterococcus faecalis, Streptococcus agalactiae
• presence of RBC can be normal