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Janus Kinase is a A. Calcium channel B. Protein that interacts with a receptor C. A...

Janus Kinase is a

A. Calcium channel

B. Protein that interacts with a receptor

C. A receptor

D. Ligand-gated ion channel

E. second messenger

Science   Anatomy-And-Physiology   
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Answer #1

Option B - PROTEIN THAT INTERACT WITH A RECEPTOR

Janus kinase is a group of enzymes hich contain JAK1,JAK2,JAK3,Tyrosine kinase 2 (TYK2). it is situated inside teh cell and bounded to the receptor presnt on the cell mebrane

It forms the JAK - STAT Pathway.it is a signalling pathway

When cytokine bind with the cytokine receptor present on the cell membrane .Receptor dimerisationwill result in the activation of JAK phosphorylation of receptor ----->STAT bind with the phosphorylated receptor ---->JAK phosphorylate the STAT ---->STAT dimer is formed (it is a second messenger ) ---->STAT dimer moves towars the nucleus of the cell ----->Bind with the DNA strand and activate gene transcription

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