Which of the following is NOT true of steroid hormones? *
1) The can pass directly through the cell membrane
2) They activate secondary messengers such as cAMP
3) They bind to protein receptor in the cytoplasm
4) They affect transcription of certain proteins
ANSWER :
The steroid hormones are lipid soluble, so diffuse across the plasma membrane of the targeted cells and bind to the intracellular receptors located in the cytoplasm or its nucleus without generating a secondary messenger like cAMP, and take comparably longer duration than non-steroidal hormone to produce desired proteins in the cells, because it affect or make changes in the genetic material (DNA) & followed by transcription and translation to generate proteins. Hence (2) is the correct answer choice.
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