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Would you consider the formation of a platelet plug in a broken blood vessel to be...

Would you consider the formation of a platelet plug in a broken blood vessel to be an example of negative or positive feedback? Explain.

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Formation of a platelet plug in a broken blood vessel is a positive feedback.

  • An injury in the blood vessel endothelium exposes the underlying collagen fibers.
  • Platelets are the blood cells responsible for blood clotting.
  • Platetes traveling thorugh the site if injury, adhere to the collagen fibers of broken blood vessel.
  • These platelets release ceratin chemicals such as adenosine diphosphate (ADP) and thromboxane.
  • ADP attracts more platets to clump over them and for a platete plug to stop the bleeding.


Positive feedback mechanism involves a response that amplify the original stimuli.

- As chemical released from the platetes attracted more platetes to skick together, this process is a positive feddback mechanism.

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