Question

Structure dictates function. A change in the structure of a molecule affects the role it plays in a pathway. A slight change at the molecular level causes disruptions at the atomic level. This error is perpetuated throughout all higher levels of organization and presents as a sign or symptom at the organismal level. In this assignment, you will explore a specific feedback loop and examine how a molecule from this homeostatic mechanism contributes to all higher levels of organization. What molecule will you pick?

Just need help picking a molecule.

Answer 1

Selected molecule = CFTR protein
Cystic fibrosis is an autosomal recessive disorder characterized by mutations in CFTR gene.
The CFTR gene codes for transmembrane protein = Cystic fibrosis transmembrane conductance regulator
This protein is involved in the production of sweat, mucucs, and digestive fluids.

Mutations in CFTR gene that alter the protein structure result in the loss of its function.
Ex: The most common mutation is ΔF508 = Deletion of Phenylalanine at 508 amino acid position.