Question

WHAT ARE SOME THERAPEUTIC PROPOSALS THAT MAY INCREASE THE IMMUNOGENICITY OF TUMORS SO THAT THEY PROMOTE...

WHAT ARE SOME THERAPEUTIC PROPOSALS THAT MAY INCREASE THE IMMUNOGENICITY OF TUMORS SO THAT THEY PROMOTE TUMORA APOPTOSIS?

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Answer #1

Therapeutic proposals to increase immunognecity  against tumour are:

Therapeutic monoclonal antibodies includes naked and conjugated antobodies.

Immuno modulating checkpoints (ICPs)

Therapeutic cancer vaccines

Dendritic cell therapy : triggers DC which is an APC in order to present tumor antigens to lymphocytes.

CAR-T cell therapy or  Chimeric antigen receptor

Rituximab, Ofatumumab and Alemtuzumab etc., aim at altering Fc regions to trigger processes such as ADCC and complement cascade.

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