WHAT ARE SOME THERAPEUTIC PROPOSALS THAT MAY INCREASE THE IMMUNOGENICITY OF TUMORS SO THAT THEY PROMOTE TUMORA APOPTOSIS?
Therapeutic proposals to increase immunognecity against tumour are:
Therapeutic monoclonal antibodies includes naked and conjugated antobodies.
Immuno modulating checkpoints (ICPs)
Therapeutic cancer vaccines
Dendritic cell therapy : triggers DC which is an APC in order to present tumor antigens to lymphocytes.
CAR-T cell therapy or Chimeric antigen receptor
Rituximab, Ofatumumab and Alemtuzumab etc., aim at altering Fc regions to trigger processes such as ADCC and complement cascade.
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