Question

What cell type is surrounded by calcified bone and secretes matrix to support bone? what is the origin of these cells?

Answer 1

Osteoblast cells are surrounded by calcified bone and secrets matrix that support bone.

Osteoblast cells are responsible for new bone formation and found in the growing part of bone such as periosteum and endosteum. Osteoblast synthesize and secret collagen matrix and calcium salts. The secreted matrix around osteoblast becomes calcified and osteoblast cells become trapped into it. Consequently the osteoblast becomes osteocytes.

Origin: Osteoblast cells arise from differentiation of mesenchymal cells in the bone marrow.