Which one is TRUE about the hormone vasopressin (also known as antidiuretic hormone, ADH)?
a. It is a peptide hormone released from the adrenal gland.
b. It triggers insertion of aquaporins into the apical membranes of collecting duct cells.
c. It promotes the excretion of more water in the urine.
d. It stimulates the excretion of K+ in the urine.
e. Its main function is to trigger the secretion of aldosterone.
Answer :- b. It triggers insertion of aquaporins into the apical membranes of collecting duct cells.
Explanation : pharmacological action of ADH or vasopressin : vasopressin binds to V2 receptor on basolateral membrane of collecting duct epithelial cell, causes activation of G protein couple receptor which activates adenylyl cyclase Leads to increase intracellCAMP which activate aquaporin translocation to the apical membrane and cause reabsoption of sodium.
Vasopressin also known as Antidiuretic Hormone which is synthesise by hypothalamus and stored into posterior pituitary gland mainly responsible for reabsoption of Sodium salt and water from the Distal convoluted tubule and littlebit from collecting duct and increses blood plasma volume...Thanks dear student
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