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What is the system responsible for controlling minute ventilation? What types of inputs does this system...

What is the system responsible for controlling minute ventilation? What types of inputs does this system receive from other areas of the body? Which of this is the most important or has the greatest impact, especially at sea level?

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Answer #1

Minute ventilation is control by

  1. Arterial CO2
  2. Hypoxia (lesser extent)

When the minute ventilation reduces pCO2 rises. The Co2 can free cross the blood brain barrier. In the CSF, CO2 combine with H20 and forms H+ ions. The central chemoreceptor situated in medulla get situated and increase the respiratory drive. Hypercapnea has the greatest impact on minute ventilation.

The peripheral chemoreceptor ( carotid body) responds to hypoxia. But they only get stimulated when the pO2 falls below 60mmhg. When the pO2 falls below 60 mmHg, the respiratory centres get stimulated. This response is blunted ( reeduced) when the pO2 falls below 30 mmhg

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