Question

1. Susan, age 8, was brought to the clinic because she had been losing weight, was very thirsty, and urinated frequently. A blood chemistry panel taken when she had not eaten for 8 hours showed an extremely high blood glucose reading of 186 mg/dL as well as other abnormal readings. A pancreatic disorder was suspected, leading to a tentative diagnosis of ______________________________________.

2. George, age 38, had been taking a high doses of oral steroid drugs for asthma for 6 years. He noted fat deposits between his shoulders and around his abdomen, muscle loss in his arms and legs, and thin skin that was prone to bruising. These symptoms are common with excess of hormone produced normally by the ____________________________

Answer 1

Question 1:-

Answer:- Diabetes mellitus (type 1-Insulin dependant DM)

Pancreas is mixed type of gland that secrets both endocrine and exocrine hormones and enzymes.

Beta cells of Langerhans produces insulin hormone which is essential to lower blood glucose for maintaining normal blood sugar levels.

Reduced secretions of insulin due to pancreatic disorder leads to type 1 diabetes mellitus.

Susan havung the following Signs and symptoms of diabetes mellitus.

• Polydipsia (excessive thirst)
• polyuria (frequent urination)
• Loss of weight due to lipolysis and
• elevated blood sugar levels( FBS 186mg/DL)

Question 2.

Answer : Adrenal cortex

• Fat deposits between his shoulders and around his abdomen
• muscle loss in his arms and legs and
• Thin skin that was prone to bruising are the side effects of steriodal hormones.

These steroidal hormones are produced by adrenal cortex.