Question

A person develops a that disease that results in the collagen fibers of the bone matrix...

A person develops a that disease that results in the collagen fibers of the bone matrix to run randomly in all directions. In addition, there is a significant drop in osteoclasts and osteoblasts. What effects would this have on bone strength, durability, and remodeling? Explain.

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Answer #1

In normal persons the bone matrix and the trabecule are arranged and organized in such a manner that they are strongest along the line of stress.This is achieved by the uniorm organisation of the collagen fibers in the matrix.The random organizatiob of the collagen in the bone matrix results in the weakening of the bone and affects its durability.The decrease in the osteoclats and the osteoblastic cells affect the remodelling of the bone.The osteoclastic cells are the cells that remove the older bone fragments.The osteoblast cells synthesise the new bone matrix and thus ensures the durabilty of the bone.Also the reduction in the quantity of trabecular bone results in the weakening of the bone.When such a weakened bone is subjected to stress,fracture can occur.

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