Question

condition swyer syndrome 1a) Describe gonad development in the individual with the condition you have chosen:...

condition swyer syndrome

1a) Describe gonad development in the individual with the condition you have chosen: 1b) _Describe the development of internal genitals in the individual with the condition you chose:

Homework Answers

Answer #1

Swyer Syndrome :

1 a) Swyer syndrome is a condition with Genotype XY with defective SRY gene, normally the SRY region of the Y chromosome is responsible for formation of Testis detrmining region and hence conversion of indifferent gonads into the testis. But in swyer Syndrome due to defect in SRY gene the gonads of this child with XY Genotype continue to develop female gonads.

Embryo with XY Genotype ---->Urogenital ridge ---> Indifferent Gonads ( 7th week) ----> a absent SRY gene ----> Ovary continue grow ---> streak ovary formed

1 b) Individual with Swyer syndrome has female external genitalia

Due to lack of SRY gene -----> Absent testis determining factor ---> absent testis ---> absent mullerian inhibiting substance ----> Mullerian duct continue to grow ---> Female internal genitalia formed ----> normal uterus and fallopian tubes are formed.

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