D) All of the above
An increase in the Carbon Dioxide concentration in blood increases the Carbonic acid concentration which makes the blood more acidic and decreases the pH. Hypoventilation, or the reduced rate of exchange of gas between the lungs and the environment will also promote an increase in blood Carbon Dioxide concentration. This concentration can also increase after increased metabolism where energy stored in Carbon-Carbon bonds is released and Carbon Dioxide is produced as a waste.
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