In contrast to excitatory postsynaptic potentials, inhibitory postsynaptic potentials…
a. Involve changes in ion flow across the cell membrane.
b. Result from neurotransmitter molecules binding to metabotropic receptors.
c. Result from neurotransmitter molecules binding to ionotropic receptors.
d. Can undergo spatial summation.
e. Result in hyperpolarization.
The correct option is E (results in hyperpolarization).
Inhibitory presynaptic neurons release neurotransmitters that bind to the postsynaptic receptors; this induces a change in the permeability of the postsynaptic neuronal membrane to particular ions. An electric current that changes the postsynaptic membrane potential to create a more negative postsynaptic potential is generated, i.e. the postsynaptic membrane potential becomes more negative than the resting membrane potential, and this is called hyperpolarisation.
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