Question

Describe what occurring, at a cellular level, with the bones in a woman in menopause.

Describe what occurring, at a cellular level, with the bones in a woman in menopause.

Homework Answers

Answer #1
  • In menopause there is decline in hormone called Estrogen.
  • Estrogen deficiency in the body causes significant bone density loss and along with compromises bone architecture
  • Estrogen deficiency in the body result in increased proliferation, differentiation, and also activation of new osteoclasts. This associated with prolongs survival of mature osteoclasts.
  • Osteoclast are mostly associated with bone breakdown.
  • Trabecular bone is most susceptible for this effect .
  • This leading to an increased risk of vertebral and wrist fractures.
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