Question

Explain the advantages of the eGFR calculation.

Answer 1

eGFR refers to estimated Glomerular filtrate rate. The advantage of using eGFR is that a single cut off value for the diagnosis of chronic kidney disease, particularly for stage 3 chronic kidney disease, would become possible, whch would enable its earlier detection, rather than by measuring serum creatinine alone. This would enable interventions that could reduce the incidence of end stage kidney failure.

The use of eGFR would enable the dosing of drugs to be optimized in people using drugs that are cleared unchanged by the kidneys.