Question

why an individual suffering from androgen insensitivity syndrome have no ovaries and uterus?? Why an invidual...

why an individual suffering from androgen insensitivity syndrome have no ovaries and uterus?? Why an invidual with AIS has very small penis?

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Answer #1

Answer

  • In androgen insensitivity syndrome, the person contains male genes (X and Y chromosomes) but exibit characteristics (phenotype) of a female.
  • Due to presence of Y chromosomes, the do contain testes but they does not descend and remians in inguinal canal.
  • There is absence of internal reproductive organs of a female (uterus, fallopian tubue, ovaries) as the person contains male genotype.
  • The receptors in the body are unresponsive to androgens (testosterone).
  • Testosterone is hormone produced by interstiital cells in testes that promotes growth of secondary sexual characteristics in males.
  • Due to insensitivity to testosterone, the peniis remain small even after puberty.
  • Due the presence of maternal estrogens in the person, certain feminine traits such as breast development occurs.
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