Question

Gillespie syndrome (GS) is a rare genetic disorder. The disorder is characterized by having part of the iris missing, ataxia, and, in most cases, intellectual disability. It is termed as a heterogenous disorder because it can be inherited either through an autosomal dominant pattern or through an autosomal recessive pattern.

Two parents are heterozygous for GS.

A. Assuming that the condition is following an autosomal dominant pattern, what are the ratios or percentages of the genotypes AND phenotypes for the possible offspring?

B. Assuming that the condition is following an autosomal recessive pattern, what are the ratios or percentages of the genotypes AND phenotypes for the possible offspring? 

C. List three examples EACH for autosomal recessive, autosomal dominant and X-linked inheritance patterns. 

Answer 1