Question

Temperature is an important factor that can regulate enzyme- mediated functions. Temperature is one of the tightly homeostatically controlled variables in the human body. What are the symptoms of loss of temperature control during a high fever? Explain why these symptoms occur based on enzyme function and cell signaling effects that are dependent on temperature.

Answer 1

1. The symptoms of loss of temperature control include

• Shivering.
• Shallow breathing.
• Mumbling.
• Weak pulse
• Drowsiness.
• Confusion.
• Loss of consciousness (in hyperthermia).

2. There is an increase in the levels of liver enzymes, creatine kinase, and white blood cells count along with low serum iron. During fever, an increase in body temperature disrupts enzyme activity. Some enzyme synthesis is stimulated, while, the activity of most of the enzymes is decreased.