describe how anti-durertic hormone affects the kidney, with specifics about what it changes and what the results are both the urine and the blood.
Anti-Diuretic Hormone (ADH)
One of the mechanism by which blood pressure is regulated is release of Anti Diuretic Hormone (ADH) from the OVLT of the hypothalamus in response to thirst or an increased plasma osmolarity.
ADH acts to increase the permeability of the collecting duct to water by inserting aquaporin channels (AQP2) into the apical membrane.
It also stimulates sodium reabsorption from the thick ascending limb of the loop of Henle. This increases water reabsorption thus increasing plasma volume and decreasing osmolarity.
As a result, urine volume is reduced and blood volume is increased.
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