Question

1. Group the following oils into; fixed, mineral, volatile and oleo-resins: almond oil, male fern oil, cod-liver oil, paraffin oil, cinnamon oil, turpentine oil, dill oil, caraway oil, soya bean oil, coconut oil, palm kernel oil and olive oil. Given that 10 ml of each type of oil is required in a formulation, calculate the quantity of water and gum required for a stable primary emulsion

2. Charles Chambas, a 90yr old retired professor reported to KNUST Hospital with feverishness and other symptoms. The doctor diagnosed Malaria and gave him this prescription in addition to some other medications.
Rx

Suppository PACLO 1 nocte x 4/7

Using the formula below, present a systematic calculation of the ingredients required. Establish a scaled formula for the preparation.

Formula

Paracetamol 25% w/w

Diclofenac 50 mg

Base to 2g

*Note DV for paracetamol is 1.2 and diclofenac is 2.15

3. Present a clear calculation and scaled formula for the preparation of 400 mL of chloroxylenol BP based on the master formula below.
Formula

Chloroxylenol50 g

Potassium hydroxide Solution (40%w/v)​​​15 ml

Sodium hydroxide​​​​​​qs

Oleic acid0.75 in 100

Castor oil​​​​​​​6.3%

Terpineol​​​​​​​5 in 50

Ethanol​​​​​​​0.20%

Purified water ​​​​​​to​1000 ml

Answer 1