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Discuss the endocrine regulation of one sex hormone: from the tropic hormone to the final sex...

Discuss the endocrine regulation of one sex hormone: from the tropic hormone to the final sex hormone



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  • Sex hormones are steroid hormones released from gonad and function to enhance reproductive process or stimulate development of secondary sexual characteristics of an individual.
  • Testosterone is a male sex hormone.
  • Hypothalamus releases a regulatory hormone called gonadotropin releasing hormone (GnRH) that acts on anterior pituitay gland.
  • GnRH stimulates anterior pituitary to release a tropic hormone called luteinizing hormone (LH).
  • LH binds to its receptors on interstital cells (Leydig's cells) in the testes. LH stimulates release of sex hormone testosterone into the bloodstream.
  • As the level of testosterone increase in blood, a negative feedback mechanism triggers hypothalamus to inhibit production of GnRH as well as anterior pituitary gland to inhibit production of LH.
  • This negative feedback helps in maintaning levels of testosterone in normal range.
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