What stimulates the endometrium to begin breaking apart?
Select one:
a. High estradiol levels
b. low progesterone levels
c. blood vessels spasm
d. A & C
e. B & C
Answer: e) B & C
Duting menstrual cycle, if the ovum is not fertilizer, the corpus luteum in the ovary involutes and causes low level of ovarian hormone secretion i.e. level of progesterone and estradiol decreases significantly.
This causes decreased stimulation of endometrial cells, resulting in endometrial involution by 65%.
During 24 hours preceding the menstruation, the tortuous blood vessels of endometrium becomes vasospastic and decreases nutrients to endometrium. This is initiated necrosis in endometrium and ultimately results into menstruation.
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