Question

​​​Is it possible for the body to reabsorb glucose in the absence of glucose carrier proteins?...

​​​Is it possible for the body to reabsorb glucose in the absence of glucose carrier proteins? Why or why not?

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Answer #1

Answer

No, it is not possible for the body to reabsorb glucose in the absence of glucose carrier proteins.

  • Glucose molecules are absorbed in the small intestine by enterocytes.
  • The plasma membrane of the cells is made up of phospholipids. It only allows the passage of small and non-polar molecules. Lipid soluble substances can easily cross the membrane.
  • Glucose (monomer of carbohydrates) is large and polar. It cannot easily move across the plasma membrane into the enterocyte.
  • Hence, there are two modes of transport in order to move glucose into the cell.

    1) GLUT : Glucose transporters are membrane embedded protein carriers that facilitates glucose transport into the cell by the process of facilitated diffusion.  


    2) SGLT : Sodium-glucose transport proteins allow secondary active transport of glucose molecules into the cell along with sodium ions.
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