A deficiency of riboflavin in the diet could lead to:
A. impairing dehyrogenation of succinate
B. disrupt complex I of electron transport chain
C. impairing carnitine shuttle
D. impairing lipid absorption
E. disruption of citrate synthase
Answer: Disrupt complex l of electron transport chain.
Explanation: Riboflavin (Vitamin B2) plays a huge role in the energy production in mitrochondria. The mitochondria consist of electron transport chain it is present in the inner membrane. The electron transport chain has five protein complexes, they are complex I, II, III,IV, V. In that complex I, III and IV helps to pump H+ ions to create H+ gradient for the ATP production. The Riboflavin deficiency affects energy production in mitochondria. Because due to this deficiency disrupt the complex I, III and IV of electron transport chain so the H+ ions is not produced for ATP production.
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