Question

A drop in blood pressure in the afferent arteriole is directly sensed by which of the following cells?

Group of answer choices

capillary endothelial cells

podocytes

granular cells

macula densa cells

Answer 1

Option a is worng as capillary endothelial cells are not specialized to detect decrease in blood pressure

Option b is wrong as podocytes will not detect a decrease in our afferent arterioles drop in BP

Option c is wrong as granular cells only will respond to the macula densa and also act in the release of renin mechanism. They cannot detect a drop

Option d is the answer as macula densa in our human   is the area of closely packed specific cells that line the wall of our distal tubule, at the point specifically where the thick ascending limb of the Loop of Henle meets the DCT. So it is situated directly above the afferent artery and when vasoconstriction of the afferent arterioles occur the. It will lead to decrease in NACL to the macula densa and this will detect a reduction in the blood pressure. This will stimulate Mechanism to increase blood pressure

:)