Question

The following is true of glucose handling in the healthy kidney?

Select one:

a. Glucose reabsorption follows the osmotic reabsorption of water

b. The maximum rate of reabsorption depends on the number of transporters

c. The amount of glucose that is excreted is greater than the amount filtered

d. It requires potassium counter-transport

Answer 1

b). The maximum rate of reabsorption depends on number of transporters .

Mostly sodium reabsorption takes place in sglut that is sodium dependent glucose transporters in the proximal convoluted tubule. It is a form of secondary active transport, which requires atp .

Threshold for glucose reabsorption is 180mg/dl . Above this level , glucose reabsorption is not possible and is sent in urine. This is due to certain number of sglut transporters available.  

In people with diabetes mellitus who suffer from increased blood glucose, sglut inhibitors are given to decrease blood glucose level . Thus it is clear that glucose reabsorption takes place due to transporters available in the tubule and it is not due to osmosis or by any other means .