Question

Calculate the # of ATP produced from 18C FFA?

Answer 1

18C free saturated fatty acid = Stearic acid
Number of Beta-oxidation cycles = 8
Number of NADH produced = 8
Number of FADH2 produced = 8

Number of acetyl CoA produced = 9
1 Acetyl CoA = 3 NADH, 1 FADH2, and 1 ATP
8 Acetyl CoA = 24 NADH, 8 FADH2, and 8 ATP

1 NADH = 2.5 ATP
1 FADH2 = 1.5 ATP

8 Acetyl CoA = (24*2.5)+(8*1.5)+8
= 60+12+8
= 80 ATP

8 NADH = 20 ATP
8 FADH2 = 12 ATP

Total ATP = 80+20+12
= 112 ATP

ATP required for activation = -2ATP

Net production of ATP = 112-2
= 110 ATP