Question

66. Bisphosphonates are drugs that prevent the loss of bone mass and are used to treat osteoporosis and similar diseases. Which of the following is the most likely mechanism of action for this drug class?

A. Osteoclast inhibition

B. Osteoblast inhibition

C. Calcitonin inhibition

D. Stimulation of parathyroid hormone

68. A chemical signal that is released from Cell A and acts on neighboring Cell B is an example of ________.

A. Dependent signaling

B. Paracrine signaling

C. Independent signaling

D. Autocrine signaling

69. In neuronal cells, the voltage-gated sodium channels are inactivated during hyperpolarization

a true

b. false

Answer 1

Answer 66: The correct option is “A. Osteoclast inhibition”.

The bisphosphonates’ mechanism of action is by the inhibiting the resorption of bone by osteoclasts.

Answer 68: The correct option is “B. Paracrine signaling”

Paracrine signaling is a chemical signal where a molecule released by one cell (Cell A) that acts on neighboring target cells (Cell B).

Answer 69: The correct option is “b. false"

During hyperpolarization, voltage-gated sodium channels open in response to a stimulus and close again.