Question

Hi, can you answer these questions.  More than one correct answers may apply to some questions.

1. Cancer cells have the following features
A. significantly elevated expression of oncogenes
B. significantly decreased expression of their suppressors
C. Certain TSGs converting to become oncogenes to promote cancer cell growth D. defying growth inhibition signals
E. reduced immune surveillance
F. increase activities of T regulatory cells

2. In gene expression analysis, fold change (FC) is calculated as tumor sample / control. So if the median value for Control is 0.20 and GBM is 0.95, FC is ________.
A. 2.00
B. 9.50

C. 4.75

D. 0.21

3. To make sure of result reproducibility, an experiment must be repeated at least _____ times conducted under the same experimental conditions but on different days from the initial experiment.
A. 1

B. 2

C. 3

D. 10

Answer 1

Question no 1

Option a is correct as oncogenens are expressed more in cancer for example in prostate cance it is expressed more

Option b is correct as mainly IGN1 and many other tumor suppressor are not expressed

Option c is false as they will not be converted to oncogens but only inactivated

Option d is true as they are not sensitive to growth inhibition signals

Option e is correct as immune surveillance reduce

Option f is correct as t regulatory cell will increase its activities by reducing antitumour immunity