Question

Which statement correctly describes the role of feedback during the ovarian cycle?

A. Maturation of another follicle is prevented in the luteal phase because the positive feedback effect of progesterone, estradiol and inhibin combined keep levels of FSH high.

B. Ovulation occurs after estradiol has a temporary positive feedback effect on the hypothalamus, causing a surge in luteinizing hormone.

C. Maturation of another follicle is prevented in the luteal phase because the positive feedback effect of progesterone, estradiol and inhibin combined keep levels of FSH low.

The amount of estradiol in the blood can be reduced by treatment with _____.

a. reductase inhibitors

b. aromatase inhibitors

c. beta-blockers

Answer 1

Answer

1. Option B) Ovulation occurs after estradiol has a temporary positive feedback effect on the hypothalamus, causing a surge in luteinizing hormone.

• Growing ovarian follicles release estrogen hormone.
• Estrogen exerts temporary positive feedback on the hypothalamus that increase GnRH secretion.
• GnRH act of anterior pituitary to promote LH surge that facilitates ovulation.

2. Option B) Aromatase inhibitors

• Testosterone in females is converted into estradiol by enzyme aromatase.
• Aromatase inhibitors prevent the conversion hence reducing estradiol levels.