Varicocele, a condition in which the pampiniform venous plexus in the spermatic cord become enlarged, can cause non-obstructive infertility in males. This condition impairs the countercurrent heat exchange within the spermatic cord, which elevates the temperature in the scrotum.
1. Pampiniform venous plexus is a venous network surrounding the
spermatic cord in males. It drains the blood from testis and
epididymis. The plexus helps regulating the temperature in the
testis through countercurrent heat exchange mechanism It helps in
keeping the blood in testicular artey surrounding the spermatid
cord cool.
The regulated temperature in testis favours the sperm
production.
2. Even a small change in temperature in the testis results in
damage to the shape or function of the sperm produced. Change in
temperature also affects sperm motility.
Temperature changes results in increased blood pooling and the
production of free radicals puts sperm under oxidative stress.
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