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Using SNP genotyping you have determined that a focal individual is a double heterozygote for two...

Using SNP genotyping you have determined that a focal individual is a double heterozygote for two loci, whereby for locus 1 it has the genotype C1T1 and for locus 2 it has the genotype A2G2. Describe an experimental design that will allow you to determine whether that focus individual is C1_A2/T1_G2 or C1_G2/T1_A2. (The corresponding question on the mini test will supply an experiment that is used and give you results but if you understand how to set up the experiment you will be prepared for that question.)

Science   Anatomy-And-Physiology   
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Answer #1

Assuming that both loci are linked, we can perform a dihybrid test cross to determine the relative arrangement of both genes


If the given individual is C1_A2/T1_G2, the frequency of progeny with this combination would be more i.e. this is the parental combination. The frequency of the recombinants would be low.

If the given individual is C1_G2/T1_A2, the frequency of progeny with this combination would be more i.e. this is the parental combination. The frequency of the recombinants would be low.


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