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list infectious diseases, which can be tested by the skin test, using Hypersensitivity reaction type IV

list infectious diseases, which can be tested by the skin test, using Hypersensitivity reaction type IV

Science   Anatomy-And-Physiology   
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Answer #1

Skin test is a method to test whether the subject is allergic to certain allergen or not.

In this test, small amount of allergen is introduced on the surface of skin and any reaction is noticed. Any reaction in the form of rash or something signify hypersensitivity.

This hypersensitivity is type 4 which is a type of cell mediated responses. These are typically provoked by intracellular microbial infections or haptens like simple chemicals applied on skin, evolve slowly and consist of a mixed cellular reaction involving lymphocytes and macrophages in particular.

Some examples are

1. Tuberculin infection (TB)

2. Cutaneous basophil hypersensitivity.

3. Contact dermititis

4. Pneumonia.

5. Chlamydia infection.

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