Describe the role of dystrophin within the motor units.
Dystrophy ----Dys = abnormal and Trophy = growth
Dystrophin gene is the largest human gene codes for protein Dystrophin .
Dystrophin is present between sarcolemma and myofilaments and it acts as cohesive protein .
It provides strength to muscle sarcolemma .
It is required for the stabilisation of protein complex at the sarcolemma known as Dystrophin associated Protein complex.
Stabilisation of complex required for anchoring between adjacent muscles cells and extracellular matrix .
It is present in all Muscles ,retina and brain .
Its absence results in DMD ( Duchenne muscular dystrophy ) and if it is defective or decreased amount of dystrophin -- BMD ( Becker's muscular dystrophy ) .
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