Question

Activity 1 Using the list of (10) events for muscle contraction. match the numbers of the...

Activity 1

  • Using the list of (10) events for muscle contraction. match the numbers of the steps from with the correct periods below in which they would occur.
  • Latent period:
  • Contraction period:
  • Relaxation period
  • Hint- 10 events of muscle contraction
  • 1. Action potential (electrical stimulation) from somatic (motor) nerve stimulates skeletal muscle fibers (cells) at neuromuscular junction
  • 2.“AP” causes the opening of Na+ channels on the sarcolemma thus causing a wave of depolarization to travel from the neuromuscular junction.
  • 3. Depolarization event is communicated deep into the sarcoplasm via t-tubules.
  • 4. Depolarization of sarcoplasmic reticulum causes the opening of Ca2+ channels and the subsequent release of calcium from sarcoplasmic reticulum
  • 5. Calcium binds to troponin, troponin molecules change shape causing tropomyosin to move off of crossbridge binding sites on actin
  • 6. Myosin crossbridges bind to crossbridge binding sites on actin
  • 7. ATPase acts on ATP in the binding site on the myosin to convert it into ADP + Pi + ENERGY
  • 8.Released kinetic energy causes a “power-stroke” which causes actin to slide over myosin (i.e. a contraction occurs)
  • 9. Sarcolemma repolarizes due to the opening of potassium channels.
  • 10.Calcium channels close and an active transport pump carries calcium back to sarcoplasmic reticulum, troponin returns to pre-calcium shape, and ATP reforms to release the actin-myosin bond

Homework Answers

Answer #1

ANSWER: LATENT PERIOD: Action potential from the somatic nerve reaches the skeletal muscle fibres at the neuromuscular junction. action potential causes openong of sodium channels and causes depolarisation. This depolarisation is communicated deep into the sacroplasm. Depolarisation of sarcoplasmic reticulum causes the relase of calcium ions. Calcium binds to troponin and exposes the binding sites of actin.

CONTRACTION PERIOD: Mysoin cross bridges are formed with the actin. ATPase converts the ATP to ADP and energy. The released kinetic energy is utilised for the power stroke which results in the shortening of muscle fibres.

RELAXATION PERIOD: Sarcolemma repolarises die to opening of potassoum channels. Calcium channels close and an active transport pump carries back the calium to the sarcoplasmic reticulum, troponin reverts back to pre calcium stage and ATP is regenerated

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