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Question. What is clinical significance of the effect of atropine on intestinal smooth muscle motility?

Question. What is clinical significance of the effect of atropine on intestinal smooth muscle motility?

Science   Anatomy-And-Physiology   
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Answer #1
  • All visceral smooth muscle that receive parasympathetic motor innervation are relaxed by atropine(M3 blockade)
  • Tone and amplitude of contractions of stomach and intestine are reduced;the passage of chyme is slowed-constipation may occur,spasm may be relieved.
  • peristalsis is the only incompletely suppressed because it is primarily regulated by local reflexes and other neurotransmitters.
  • Cholinergic antagonism with atropine reduce the antral contractility and slow down antral contractility.
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