Question

Along with the degenerative loss of dopamine neurons in Parkinson’s disease, we also see a loss of?

A. Serotonin in striatum

B. Serotonin in nucleus accumbens

C. Serotonin in hypothalamus

D. Serotonin in thalamus

Answer 1

Answer:

Option A (Serotonin in striatum)

Explanation: Parkinson’s disease is a neurological disorder within the central nervous system which leads to a progressive depletion in the neurotransmitters dopamine. Due to this depletion, the movements of the body get affected and also affect the muscle rigidity also called as tremors.

Also, in the disorder, the nuclei of the corpus striatum located within the basal ganglia get degenerated. Due to this there takes place a gradual depletion of the neurotransmitter named serotonin. Due to this depletion taking place, the neural synapse rate also gets affected accounting for a lowered movement within the body.

Furthermore, according to a study being conducted, it has been proposed that in the disorder, nearly 57% of the total neural loss occurs thus depleting the levels of the neurotransmitter; serotonin