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Mutations in cellular level may cause changes in the cellular function, and decrease or an increase in the mass of tissues. Even abnormal apoptosis in a single cell may lead to the development of tumors.
Tissues are made of different types of cells. Therefore, if any part of the tissue is not created well such as that part contains more or fewer cells. Anatomically the tissue will appear changed structure than the normal tissue.
At the organ level, if some tissues are in more or no amount, it will show the structural abnormality in organs, such as skin tumors.
Organ systems are made of organs. Therefore, sometimes, any organ may be abnormally large or small. This is also anatomically abnormal.
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