Question

Explain the role of oxaloacetate, palmitoyl-CoA, Fumarate and Alanine in connecting metabolic pathways. For each molecule, explain which pathways are connected, how the molecule connects them, and in which physiological state that connection is required.

Answer 1

Here .

FATTY ACID OXIDATION

KREB CYCLE

GLUCONEOGENESIS

ALL PATHWAYS ARE USED .

1.FATTY ACID OXIDATION

Palmitic acid is long chain 16 carbon fatty acid .

Palmitic acid form pamitoyl COA on CO Acylation

Then on B oxidation from acyl COA and Acetyl COA

2. KREB CYCLE  

Acetyl CoA goes into kreb cycle form Oxaloacetate .

3 .GLUCONEOGENESIS

OXALOACETATE conversion to Pyruvate by Pyruvate carboxylase enzyme .

4. Alanine amino acid ENTER to kreb through .

Pyruvate formation bybalanine transaminase