There is difference in oxygen content of blood on the two sides of the heart as both the sides of the heart show different function.The right side of the heart(Right atria and right ventricle) get blood from veins which is poor in oxygen and rich in carbon dioxide and pump it to the lungs for gaseous exchange where the blood again gets rich in oxygen and goes into left side of the heart(Left atria and left ventricle) where it is pumped into the body through arteries.
As both sides are functioning different , dual circulation is found in heart which makes difference in oxygen content of blood on the two sides of the heart.
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