Question

Explain the difference between Exogenous and Endogenous antigens presented by MHC class I and class II

Explain the difference between Exogenous and Endogenous antigens presented by MHC class I and class II

Science   Anatomy-And-Physiology   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

Exogenous antigen presentation- when the exogenous antigen enters the body it undergoes endocytosis by some antigen presenting cells such as macrophages, dendritic cells, or B cells. After endocytosis the antigen is degraded into peptide fragments in endoplasmic reticulum and attached with MHC 2 molecule. This complex of MHC and peptide is then transported to cell surface which is then presented to helper T-cell.

Endogenous antigen presentation- Antigen produced in host cell either it be viral cell protein or some abnormal protein made by cancer cells. All the nucleated cells in body express MHC 1 molecule so these endogenous antigens after degradation into peptide are associated with MHC 1 molecule and this complex is transferred to cell surface which is then presented to CD8 t cell (cytotoxic t cell).

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
11. Viral antigens are loaded onto MHC class I receptors via the _______________ pathway. A. intrinsic...
11. Viral antigens are loaded onto MHC class I receptors via the _______________ pathway. A. intrinsic B. extrinsic C. endogenous D. exogenous E. complement
Explain the difference between endogenous and exogenous variables.
Explain the difference between endogenous and exogenous variables.
Which of the following statements describe Class I MHC molecules, and which describe Class II MHC...
Which of the following statements describe Class I MHC molecules, and which describe Class II MHC molecules? This molecule is expressed on all nucleated cells. This molecule interacts with proteins expressed on the surface of Cytotoxic T cells. This molecule is expressed on the surface of Antigen presenting cells. This molecule is important for activating Helper T cells This molecule is expressed on the surface of B cells. This molecule binds to antigens that come from primarily intracellular pathogens A....
What are the primary functions of both CD4 and CD8 T cells? Which MHC molecules do...
What are the primary functions of both CD4 and CD8 T cells? Which MHC molecules do they utilize (MHC Class I or II) and what types of antigens do they respond to (endogenous or exogenous)? Why is this important to their function?
Briefly explain difference between endogenous and exogenous variables and provide one example of each type in...
Briefly explain difference between endogenous and exogenous variables and provide one example of each type in the supply and demand model. (Suggested length is 3 sentences)
Describe antigen processing .How does the process differ from endogenous and exogenous antigens? (20 marks)
Describe antigen processing .How does the process differ from endogenous and exogenous antigens?
The distinction between endogenous and exogenous variables is: a. dependent on the distribution of the variables,...
The distinction between endogenous and exogenous variables is: a. dependent on the distribution of the variables, i.e., when they are normally distributed, they are exogenous, otherwise they are endogenous. b. whether or not the variables are correlated with the error term. c. dependent on the sample size, i.e., for n sufficiently large, endogenous variables become exogenous. d. that exogenous variables are determined inside the model and endogenous variables are determined outside the model.
Codominance of MHC alleles plays a part in making sure that a diversity of antigens can...
Codominance of MHC alleles plays a part in making sure that a diversity of antigens can be presented by each individual? Explain how?
Please explain this •Class I MHC Gene •Glycoprotein expressed on all nucleated cells. •Major function to...
Please explain this •Class I MHC Gene •Glycoprotein expressed on all nucleated cells. •Major function to present processed Ags and T C. •Found in regions A, B, and C (K and D in mice). •Class II MHC Gene •Glycoprotein expressed on Macrophages, B-cells, DC’s. •Major function to present Ags to T H. •Found in regions DR, DP, and DQ (IA and IE in mice) •Class III MHC Gene •Products that include secreted proteins that have immune functions. •Ex) Complement system.
Explain the important difference between the Solow growth model and any of the endogenous growth models.
Explain the important difference between the Solow growth model and any of the endogenous growth models.
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT