Question

how action potential of nodal cells are different from the action potential of cardiac muscles cells?

how action potential of nodal cells are different from the action potential of cardiac muscles cells?

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Answer #1

The action potentials of nodal tissue are distinct from those of atria and ventricular myocytes . The complement of ionic currents present in nodal cells results in a less negative resting membrane potential compared with atrial or ventricular myocytes.

The regional difference in action potentials is a result of differences in the number and types of ion channels present in the heart. Unique sets of ionic currents are active in pacemaking and muscle cells, and the relative contributions of these currents may vary in the same cell type in different regions of the heart.

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