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What is the equilibrium potential of chloride ions in a mammalian neuron when the ion concentration...

What is the equilibrium potential of chloride ions in a mammalian neuron when the ion concentration inside the cell is 10 mM and their concentration outside the cell is 140 mM? Give your answer in mV, rounded to the nearest hundredth.

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Answer #1

  • Given (Cl)o = 140 mM
  • (Cl)i = 10 mM
  • Temperature (of normal human) = 37℃ = 310 K
  • Z (for Cl) = -1

Eion = (8.31×310)/(-1 × 96500) ln (140/10)

Eion = - 0.0267 × ln 14 = 0.027 × 2.639 = - 0.07461 V or - 70.461 mV

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