Why does osmotic concentration decrease in the thick ascending limb of the nephron loop?
A. Urea is transported out of the tubule. |
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B. Na+ and CI- are actively transported out of the tubular fluid. |
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C. The thick ascending limb is permeable to water. |
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D. Both A and B are correct. |
Ans:- D) both a and b
The thick ascending limb of the loop of Henle is permeable to urea (and sodium) but not to water.
As water moves from bottom to upward part of ascending Limb of loop of henle sodium chloride and potassium diffuses out of the ascending Limb of loop of henle due to presence of Sodium Potassium Chloride cotransporter as ascending Limb of loop of henle is not permeable to water so show only salutes are are moving out of the Tubular fluid and water remain inside the loop of henle causing its decrease osmolarity urea is also permeable to ascending Limb of loop of henle.
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